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Method and Materials
 

Ultrasonic liquid processing is a highly valuable methodology in the laboratory. High intensity (20 kHz range) ultrasonic generation is sufficiently powerful to achieve useful liquid processing in a wide variety of applications. Everything from lysis of E. coli cells to spot cleaning of dirty labware can be performed easily, quickly and reproducibly.

HOW ULTRASONIC LIQUID PROCESSING WORKS

The ultrasonic generator produces an electrical signal at a particular frequency.
 
The converter/transducer transforms the electrical signal into mechanical vibration.
 
The tip of the horn/probe expands and contracts at the same frequency as the electrical signal through a prescribed amplitude (distance)

In liquid, the rapid (i.e., 20 kHz) vibration of the horn probe tip causes cavitation, the formation and violent collapse of microscopic bubbles.

The collapse of the thousands of cavitation bubbles releases tremendous energy into the liquid form of shock waves.

Objects and surfaces that are within or near the cavitation field are "processed" by the released energy.

The choices of a generator (and transducer) and horns/probes are matched to the volume, viscosity and other parameters of the particular application.

SOME SPECIFIC APPLICATIONS

  • Lysis of bacterial, fungal, mammalian and other types of cells
  • Mixing of compounds and solutions
  • Improving solubility
  • Generation of fine emulsions
  • Catalyzing difficult reactions
  • Degassing of solutions
  • Analyzing soil samples
  • Cleaning

MISONIX EQUIPMENT

Our Ultrasonic Generators ( two models, one for larger and one for smaller volumes) are highly sophisticated electronic devices that automatically adjust the power level to meet the the level of resistance produced by the specific application.

Our Transducers utilize carefully selected piezo-electric crystals to transform the electrical signal to mechanical vibration.

Our Horns/Probes are crafted from high quality titanium or aluminum.

 

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